2016

In this week’s episode of The Dr. Ardis Show, Dr. Bryan Ardis dives deep into the topic of Heart Failure, discussing its causes, risk factors, and most importantly, what you can do proactively to prev

DuckDuckGo. Privacy, Simplified.

DuckDuckGo. Privacy, Simplified.

Explore leucovorin's potential benefits for autism, its scientific background, research findings, and importance of personalized treatment approaches.

Protein, exercises, and key mechanisms to boost your brain with muscle. Get the E-book!

(NaturalHealth365) Discover how to support brain health naturally with key nutrients, lifestyle changes, and powerful antioxidants.

(NaturalHealth365) Harsh hair dye chemicals have been shown to increase the risk of cancer. Discover a non-toxic way to eliminate grey hair.

Mucopolysaccharidosis type II (MPS II) is caused by a deficiency in iduronate-2-sulfatase (Ids), an enzyme that catabolizes glycosaminoglycan (GAG). Ids insufficiency results in the accumulation of GAG in various organs, ultimately resulting in multisystemic disease. Trehalose, a non-reducing disaccharide, has shown protective effects against various diseases. However, its potential utility through oral administration in MPS II has not yet been explored. In the present study, to investigate the efficacy of oral trehalose in Ids-knock-out (KO) mice, Ids-KO and wild type (WT) mice were treated with 2% trehalose dissolved in distilled water ad libitum for 24 weeks. Histological analysis revealed that almost all tissues from Ids-KO mice exhibited abnormal changes, including large vacuolization, inflammatory cell infiltration, and GAG deposition. However, oral administration of trehalose significantly suppressed GAG levels, vacuolization, inflammation and apoptosis in the spleen and brain. Additionally, oral trehalose considerably improved cognitive functions, such as short-term spatial learning and working memory, alongside limited improvements in walking capacity in Ids-KO mice. These results suggest that oral trehalose can reduce GAG accumulation, vacuolization and the number of apoptotic and inflammatory cells in pathological tissues including the brain, ultimately considerably improving spontaneous alteration behavior and could be a promising treatment option for MPS II.

(NaturalHealth365) Did you know that heartburn drugs can cause kidney damage in 50 percent of users - without any warning signs?

Could long sought-after support for type 1 diabetes be as close as your kitchen cupboard? An accumulating body of scientific research appears to point in exactly that direction

Ivermectin 12 mg capsules for parasitic infections in humans and animals. Investigational use in cancer treatment. 100 capsules per bottle. High quality and purity.

Hempseeds, from the Cannabis sativa plant, and its derivates are a versatile food option for various dietary preferences. Due to their aminoacidic profile, researchers have studied the presence of bioactive peptides in hempseed proteins. In this study, the water-soluble fraction of hempseed protein was extracted, and the derived peptides were analyzed. The investigation focused on their biological function, particularly their antioxidant activity. Several biological functions have arisen, such as angiotensin-converting enzyme inhibition activity, dipeptidyl-peptidase IV, dipeptidyl-peptidase III inhibition, and ubiquitin-mediated proteolysis activation. The hydrolysates show greater 2,2-azinobis-[3-ethylbenzothiazoline-6-sulphonic acid (ABTS) radical scavenging activity compared to the proteins (97.95 ± 4.48 versus 81.04 ± 10.63). Furthermore, the impact of these proteins and peptides on the U937 cell line was evaluated to assess cell viability and their potential role in modulating inflammation associated with gastrointestinal autoimmune diseases. Protein treatment resulted in a significant reduction in cell viability, as opposed to hydrolysates, which did not affect it.