2016

Dr. Nojima’s mineral breakthrough, the patients who got better, and the disinformation machine that moved to shut it all down. *This chapter is not paywalled**

Groundbreaking research shows how one natural fat can suppress fungal overgrowth, restructure starch metabolism, and support biological sovereignty.

From contaminated aquifers to “dead” purified water, this is the chapter where the crisis becomes clear—and the solutions begin. *Note to free subscribers: this chapter is not paywalled.

Landmark analysis identifies 12 natural compounds with broad anti-cancer activity, consistently targeting core pathways such as cell death, immune evasion, metabolic dysfunction, and metastasis.

Is there a demonic plan behind the transformation of Tucker Carlson, Candace Owens, & others? Could it center a supernatural encounter in the middle of nigh...

A card catalog of censored science and expertise. Categorized, excerpted, and searchable

Background Glucosamine is a commonly used ‘over the counter’ dietary supplement. Previous research has identified an association between glucosamine use and several positive health outcomes. However, a plausible biological mechanism for these associations has not yet been identified, meaning the causality of these relationships remains unclear. A protective effect of glucosamine on the vascular endothelium has been suggested as one such possible mechanism. Albuminuria is an early marker of endothelial dysfunction within the kidney and is associated with progression of kidney disease and adverse cardiovascular outcomes. In order to provide insights into the potential biological mechanisms underlying a protective association of glucosamine use with health outcomes, we evaluated evidence for an association between glucosamine use and albuminuria in UK Biobank (N=436 200). Methods Univariable and multivariable ordinal logistic regression were performed to evaluate evidence for an association between self-reported glucosamine use and albuminuria (measured as urine albumin creatinine ratio (uACR) categories). As a secondary analysis, we performed Mendelian randomisation (MR) to demonstrate the difficulties in inferring causality in this relationship using currently available data, using summary genetic data from UK Biobank and CDKGen (N=67 452). Results We found that people who used glucosamine were more likely to be in a lower uACR group (OR 0.81, 95% CI 0.80 to 0.83, p<2.2×10−16). This association was robust to sensitivity analyses and was maintained after adjustment for age, sex and measures of obesity. In our MR analysis, we found little evidence for an association of genetically proxied glucosamine use on albuminuria (change in log uACR (mg/g) per SD change in genetic liability=1.11, 95% CI −3.01 to 5.23, p=0.60). Conclusions We found that detectable albuminuria was common in UK Biobank participants and we are the first to show that use of glucosamine supplements was associated with lower levels. Though this fits with a plausible biological role of the vascular endothelium in a potential protective effect of glucosamine use on many health outcomes, whether this relationship is causal or confounded remains unclear. We further discuss the inherent difficulties in using genetic instruments to proxy supplement use in MR analyses and highlight the need for a genome-wide association study of measured circulating glucosamine levels. Data may be obtained from a third party and are not publicly available. Data are available from the UK Biobank () for researchers who meet the criteria for access to deidentified UK Biobank data.

Lung cancer is one of the most common cancers, resulting in numerous deaths worldwide. It is classified into small-cell lung cancer and non-small cell lung cancer. The non-small cell lung cancer accounts for approximately 80% of all cases. Current chemotherapeutic treatments, often limited by severe side effects and toxicity to healthy tissues, underscore the need for more effective and better-tolerated therapies. Natural compounds, such as fucoidan, a sulfated polysaccharide extracted from brown algae, offer a promising avenue for developing such treatments due to their ability to eliminate tumor cells, delay tumor growth, and improve the effectiveness of chemotherapy drugs. Furthermore, fucoidan has received much attention in cancer therapy owing to its various advantages, including its abundance in natural sources, unique structural features of sulfate groups capable of interacting with receptors involved in cancer suppression, and its ability to modulate multiple cancer pathways. This review provides an overview of key factors contributing to lung cancer development, introduces the chemical structure and classification of fucoidans, and comprehensively examines their antilung cancer mechanisms, including apoptosis induction, proliferation inhibition, metastatic suppression, and immune modulation at the cellular level. Drug discovery and preclinical studies evaluating fucoidan in lung cancer therapy are summarized and discussed. Finally, current challenges and future research directions for fucoidan-based drug design are addressed, focusing on the steps necessary to translate promising preclinical findings into clinical applications.

Saudi Arabia wants a credible pathway to Palestine, (a Palestinian state), before they will sign on to the Abraham Accords and normalize relations with Israe...

Scientific Reports - Investigating fucoidan blend supplementation and resistance training in humans: a parallel randomized controlled trial design

D-allulose is a rare monosaccharide with established safety and documented biological functions, whereas its potential effects on ulcerative colitis r…

Doomscrolling, zombie scrolling, and dopamine-driven streams of low-quality content are producing measurable cognitive impairment across an entire generation.

The same element long accused of harm is, in truth, one of nature’s oldest purifiers and an invisible architect of life.

I analyzed every major mineral source so you don’t have to. The results may make you rethink your entire trace supplement shelf and why composition matters more than marketing.

Indeed, some recent research suggests that improvements in memory from cognitive training are driven by increases in BDNF, and it may also be the case that part of the benefit provided to people from antidepressants is through BDNF increases. The good news is that independent of pharmaceuticals, research suggests basic lifestyle changes can increase BDNF levels

Dr. Peter McCullough, John Leake, and Nic Hulscher Hold Press Conference on the Historic Reversal

Lactobacillus johnsonii is a commensal bacterium that has been isolated from vaginal and gastrointestinal (GI) tracts of vertebrate hosts, including humans, ...

BackgroundLactobacillus johnsonii (L. johnsonii) is a lactic acid-producing probiotic, possessing the potential to modulate intestinal microbiota balance, wh...

Bile Salt Hydrolase (BSH) is a bacterial enzyme (EC 3.5.1.24) that initiates the crucial deconjugation of bile acids (BAs), a process necessary for th…

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In a cohort that was 94% vaccinated, every participant had amyloid microclots —the same pathology behind the large white fibrous clots now being pulled from corpses worldwide.

How vaccines became the holy water of Western civilization

Glyphosate-Based Herbicide (GBHs) are widely used worldwide, this study investigated the ameliorative effect of Aloe Vera against GBHs hepatic toxicity in ra...

Daniel's vision contains four separate clocks to Jesus's Return. Not just the 70 Weeks that most Christians know, but 3 other timers, all counting down to sh...